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Study for the mechanisms of recurrent urinary tract infections with postmenopausal women with Zhuolin Granules from the perspective of microecological changes

Study for the mechanisms of recurrent urinary tract infections with postmenopausal women with Zhuolin Granules from the changes of urinary and intestinal microbiota

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR1900002671
Enrollment
Unknown
Registered
2019-10-15
Start date
2019-01-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Urinary Tract Infection

Interventions

Sponsors

Changzhou Affiliated Hospital of Nanjing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. meeting the diagnosis criteria of urinary tract infection; 2. symptomatic urinary tract infection (urinary frequency, urgency, dysuria; at least two symptoms); 3. had a documented history of three or more culture-confirmed symptomatic episodes of uncomplicated UTI in the previous year; 4. menopausal (without menstruation for at least 12 months); 6. sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Complicated urinary tract infections caused by urinary tract obstruction, indwelling catheter, diabetes mellitus and impaired immune function; 2. Urethral syndrome, asymptomatic bacteriuria; 3. Combined with serious heart, liver, kidney, hematopoietic system, endocrine, respiratory system and other diseases, malignant tumors or serious diseases affecting their survival; 4. Non-bacterial infections (fungi, mycoplasma, chlamydia, parasites); 5. Allergic constitution, or known drug allergy patients used in this test; 6. Immune stimulation therapy was administered within one month before admission; 7. Patients participated in clinical trials of other drugs or antibiotics or probiotics were used in previous three months.

Design outcomes

Primary

MeasureTime frame
urine culutre;Urinalysis;Urine microbiota;Fecal microbiota;

Countries

China

Contacts

Public ContactZhu Meifeng

Changzhou Affiliated Hospital of Nanjing University of Chinese Medicine

Dr_Sandy@163.com+86 15995031950

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026