Knee osteoarthritis
Conditions
Interventions
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Preoperative diagnosis of simple knee osteoarthritis; 2. Aged between 40-75 years; 3. Regular review as required, with good compliance and ability to cooperate with the research of the subject.
Exclusion criteria
Exclusion criteria: 1. With abnormal physical deformity, ligament injury around the knee joint, abnormal muscle strength and other abnormal physical factors; 2. Combined with tumor or systemic metabolic disease; 3. Long-term use of hormones; 4. Non-steroidal drugs were used 1 week before surgery; 5. Other treatments were used during treatment; 6. Suspected of a systemic or local infection; 7. The condition is critical and may be exacerbated by the inclusion of observations; 8. Those who are allergic to non-steroidal anti-inflammatory drugs; 9. All patients at risk of bleeding, eg. previous gastrointestinal bleeding or peptic ulcer. 10. Cannot make an accurate assessment of the effectiveness and safety of the drug; 11. Patients with diabetes or patients with skin lesions or skin diseases. 12. Other traumatic diseases were found during follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperatively 3 days (post-op D1/2/3), 3 groups of patients with resting pain and active pain in the knee: using VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 week postoperatively, comparison of knee function scores in 3 groups: HSS score;Differences in drug concentration between blood, knee joint fluid, subcutaneous tissue and deep tissue indomethacin in the three groups on the day of surgery; | — |
Countries
China
Contacts
Public ContactXuewei Cao
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed