Rheumatoid Arthritis
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Criteria for RA: (1) patients with definite diagnosis of rheumatoid arthritis; (2) patients have no serious primary diseases, chronic wasting diseases and mental disorders such as cardiac, cerebrovascular, liver, kidney and hematopoietic system; (3) patients with knee joint pain accompanied by destruction need knee joint replacement; (4) patients have better compliance and can complete the whole course of treatment.
Exclusion criteria
Exclusion criteria: (1) the patients refused to undergo knee replacement; (2) the patients have surgical contraindications; (3) those with poor compliance or who are participating in other drug trials; (4) patients who have not been treated with this test protocol as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VEGFA;INOS;HIF-1 alpha; | — |
Countries
China