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Study on Brain Network of Antidepressant Effect Mechanism with Acupuncture

Study on Brain Network of Antidepressant Effect Mechanism with Acupuncture

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR1900002656
Enrollment
Unknown
Registered
2019-10-10
Start date
2019-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Experimental group:Electroacupuncture

Sponsors

Guangdong Province Traditional Chinese Medical Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Participants who meet the diagnostic criteria of Depressive Disorder Due to Another Medical Condition according to DSM – 5 from the American psychiatric association,and the level of depression conforms to moderate to mild depression (F32.0) or moderate depression (F32.1) according to the International Classification of Diseases Coding Table (ICD-10) or whose HAMD-17 score 8-22; 2. Participants was diagnosed with a first appearance depressive disorder; 3. Participants who have not received hormone replacement therapy or anti-depression medication within 3 months; 4. Participants aged 18 to 40 years; 5. Willingness to participate in the trial and having provided written consent.

Exclusion criteria

Exclusion criteria: 1. Item 4 or 5 of Beck Suicide Ideation Scale (SSI) is not answered "No"; 2. The depression factors in SCL-90 score failed to exclude the suicidal tendency (>26); 3. Participants had participated in other clinical trials within 4 weeks before the start of this study; 4. Participants who had severe diseases of other systems require treatment; 5. Participants had brain diseases and judgment ability was abnormal (Wechsler Adult Intelligence Scale<90); 6. Desiring to conceive,pregnant or lactating women; 7. Participants who had been taking anti-depression and anti-anxiety medication for 2 weeks before the trial; 8. Participant who install a pacemaker or an artificial joint.

Design outcomes

Primary

MeasureTime frame
HAMD-17;

Secondary

MeasureTime frame
Electroencephalogram;

Countries

China

Contacts

Public ContactWu Qian

Guangdong Province Traditional Chinese Medical Hospital

wuqian@vip.163.com+86 13580323354

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026