paroxysmal atrial fibrillation with type 2 diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients who were diabetes based on the criteria for diabetes in 1999 WHO, received insulin or oral therapy with diet; 2) Patients have recent onset AF or paroxysmal AF (duration of current episode is <48 hours), need to restore sinus rhythm; 3) Blood pressure above 90 /60 mmHg; 4) Stable hemodynamics, without electrical cardio version therapy; 5) Aged 18-80 years, eligible to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with structural heart disease: rheumatic heart disease, chronic pulmonary heart disease, viral myocarditis, congenital heart disease, after pacemaker implantation; 2) Combined effects of hyperthyroidism, pre-excitation syndrome, atrioventricular (AV) block, etc.; 3) Patients were diagnosed with acute coronary syndrome within 6 months; 4) Severe combined primary liver, kidney, hematopoietic system and endocrine system deficiency; 5) New York Heart Association (NYHA) Class>III heart failure; 6) AV Conduction block and QT-interval prolongation (Q-Tc > 480 ms), bradycardia (heart rate < 50 beats min ) Holter monitoring pauses longer than 2 s; 7) Pregnant or breast-feeding, allergic or psychiatric illness; 8) Patients with advanced disease; 9) Patients are allergic to Amiodarone or Exenatide; 10) Patients are or have been treated with amiodarone or other GLP-1R agonist.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The duration of AF;The average time of conversion;FS;Blood sugar levels;LVEF;The frequency of AF; | — |
Countries
China
Contacts
Jiangsu Province Hospital on Integration of Chinese and Western Medicine