AE-IPF
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Henan University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) A confirmed diagnosis of AE-IPF; (2) Aged between 40 and 80 years; (3) Without participations in other interventional trials in the previous one month; (4) With the informed consent signed.
Exclusion criteria
Exclusion criteria: (1) Pregnant and lactating women; (2) Dementia, mental disorders and reluctant partners; (3) Complicated with heart failure (NYHA Class IV), or unstable hemodynamics, or hypertension (Grade-4), or serious cardiac arrhythmias (e.g., ventricular tachycardia, paroxysmal supraventricular tachycardia, ventricular flutter and ventricular fibrillation); (4) Complicated with Other diseases (e.g., bronchiectasis, active tuberculosis, pneumothorax, Pleural effusion, pulmonary thromboembolic, or Neuromuscular diseases affect respiratory movement function); (5) Treated outside the hospital for more than 7 days; (6) Need to carry out invasive mechanical ventilation respiratory failure; (7) Complicated with serious hepatic and renal diseases (liver cirrhosis, portal hypertension, bleeding of varicose veins, dialysis, or renal transplantation); (8) Bedridden for various reasons; (9) Allergic to the used medicine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the treatment failure rate;mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| intubation rate;acute exacerbation rate;mMRC;the length of hospital stay;quality of life;arterial blood gas analysis; | — |
Countries
China
Contacts
Public ContactZhang Hailong
The First Affiliated Hospital of He'nan University of Chinese Medicine
Outcome results
None listed