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Study for the clinical efficacy of sequential Chinese medicine colonic lysis based on improving intestinal micro-ecology to improve chronic kidney disease

Study for the clinical efficacy of sequential Chinese medicine colonic lysis based on improving intestinal micro-ecology to improve chronic kidney disease

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR1900002616
Enrollment
Unknown
Registered
2019-09-24
Start date
2019-10-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

Sponsors

Wangjing Hospital, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Comply with the diagnostic criteria of chronic kidney disease and the standard of Chinese medicine syndrome. 2. Age between 30 and 75 years old (including 30 and 75 years old). 3. The patient refused renal replacement therapy and insisted on conservative treatment. 4. Follow-up clinics and hospitalizations, good compliance, and informed consent.

Exclusion criteria

Exclusion criteria: 1. Chronic kidney disease has undergone long-term maintenance hemodialysis. 2. Vital signs are not stable and need to rely on drugs, ventilators and other maintainers. 3. There are urgent dialysis indications such as hyperkalemia, acidosis, and uremia encephalopathy that are difficult to correct. 4. There are serious cardiovascular and cerebrovascular diseases, liver diseases, blood system diseases, combined with severe heart failure, infection has not yet eased. 5. Who are currently taking glucocorticoids or immunosuppressants. 6. Severe intestinal disease can not tolerate the enema. 7. Patients with chronic diarrhea and hemorrhoids, anal fissure, and intestinal surgery. 8. The purpose of hospitalization is clear to start hemodialysis or peritoneal dialysis.

Design outcomes

Primary

MeasureTime frame
Estimating glomerular filtration rate;Serum creatinine;Uric acid;Intestinal flora;D-lactic acid;Urea nitrogen;Serum endotoxin;Indole sulfate;

Countries

China

Contacts

Public ContactTongxia Li
litongxia0711@126.com+86 010-84739029

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026