Knee Osteoarthritis
Conditions
Interventions
Sponsors
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine.
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 45-65 years, male or female; 2. Knee pain more than 6 months;; 3. KL (Kellgren-Lawrence) grade II or III in recent 12 months; 4. NRS >= 4 in the past one week; 5. Right handedness; 6. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Surgery history of knee or waiting for surgery (knee replacement or knee arthroscopy); 2. History of arthroscopy within 1 year or intra-articular injection within 6 months; 3. Knee pain caused by other diseases (such as joint bodies, severe effusion of joint cavity, infection, malignant tumors, autoimmune diseases, trauma, etc.); 4. Severe acute/chronic organic or mental diseases; 5. Coagulation disorders (such as hemophilia, etc.): 6. Pregnant women, pregnant and lactating women; 7. Claustrophobia or with a cardiac pacemaker, metal products and other contraindicated by MRI examinations; 8. Severe skull anatomical asymmetry or definite lesions were found in magnetic resonance scanning; 9. History of receiving acupuncture or massage treatment within 1 month; 10. Allergy to needles and alcohol, or fear acupuncture needles; 11. Participation in another clinical study in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate;Brain Functional Activity ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of people taking rescue medications ; Adverse events about acupuncture ;Western Ontario and McMaster Universities Osteoarthritis Index ;Oxytocin;Gene polymorphism;Blind evaluation;Stanford Expectations of Treatment Scale ;State-Trait Anxiety Inventory-State; | — |
Countries
China
Contacts
Public ContactCunzhi Liu
School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine.
Outcome results
None listed