Knee osteoarthritis
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Early knee osteoarthritis; 2. Aged <= 60 years; there is no limit to men and women; 3. Cartilage injury was found on MRI of knee joint; 4. Agree and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Secondary KOA; 2. Those complicated with cerebrovascular, liver, kidney, mental diseases and other serious diseases; 3. Suffering from joint tuberculosis, tumor, infectious arthritis, rheumatoid arthritis, ankylosing spondylitis, gout, psoriasis and other systemic diseases; 4. There is a history of knee joint trauma, fracture and operation; 5. Pain attack accompanied by fever; 6. The course of disease is not self-limiting and progressive aggravation; 7. Patients who are unable to complete case data collection and have poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| magnetic resonance imaging T2-mapping imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Countries
China
Contacts
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine