Recurrent Spontaneous Abortion
Conditions
Interventions
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 2 or more spontaneous abortions occurred within 12 weeks gestation
Exclusion criteria
Exclusion criteria: 1) The genetic abnormality of both husband and wife, the male semen abnormalities lead to RSA; 2) severe diseases such as cerebrovascular, hepatic, renal and hematopoietic system; 3) Excluding uterine fibroids, uterine malformations and other anatomical abnormalities leading to RSA; 4) Excluding endometrial receptivity abnormalities such as intrauterine adhesions leading to RSA; 5) Exclude congenital prethrombotic state such as coagulation factor gene mutation leading to RSA; 6) Exclude acquired prethrombotic state such as antiphospholipid syndrome leading to RSA; 7) Exclude endocrine diseases such as polycystic ovary syndrome and gestational diabetes leading to RSA; Those who are allergic to research drugs, have a history of drug-induced liver damage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy outcome; | — |
Secondary
| Measure | Time frame |
|---|---|
| Distribution of Treg lymphocytes in endometrium during luteal phase;cytokines in peripheral blood;population of T lymphocytes in endometrium during luteal phase;population of T lymphocytes in peripheral blood;Distribution of CD8+T lymphocytes in endometrium during luteal phase; | — |
Countries
China
Contacts
Public ContactGuoging
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed