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Study for the effect of Danlou tablet on gut microbiota of CHD patients and its metabolomics

Study for the effect of Danlou tablet on gut microbiota of CHD patients and its metabolomics

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR1900002563
Enrollment
Unknown
Registered
2019-09-02
Start date
2019-09-15
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Danlou tablet:Oral Danlou tablets
CHD control group:placebo

Sponsors

Traditional Chinese Medicine Hospital of Tailai County, Qiqihar City, Heilongjiang Province
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged between 40-85 years; 2. Meets the diagnostic criteria for stable coronary heart disease; 3. singed the consent form.

Exclusion criteria

Exclusion criteria: 1. Combined with Congenital heart disease, rheumatic heart disease, unstable angina pectoris; 2. Combined with Valvular disease, suspected major artery dissection, arrhythmia, acute heart failure, moderate to severe pulmonary hypertension, acute pulmonary embolism and other serious cardiopulmonary dysfunction; 3. Combined with Severe liver and kidney dysfunction, immune diseases; 4. Combined with acute infection; 5. Patients who used antibiotics, other lipid-lowering and blood-glucose lowering drugs and other Chinese medicines before 2 weeks and during the experiment; 6. Involuntary patients, poor compliance; 7. Participated in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Angina pectoris;LPS, TMAO;TC TG HDL LDL;IL-1ß, IL-6, IL-10, TNF-alpha;echocardiography;gut microbiota;Blood glucose;Electrocardiogram;Apolipoprotein A1 and B;Symptoms of traditional Chinese medicine;Hematology and stool metabolomics;

Countries

China

Contacts

Public ContactLi Yuhong

Tianjin University of Traditional Chinese Medicine

yhltcm@126.com+86 13352057819

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026