Primary hyperlipidemia with carotid atherosclerosis
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Accord with the diagnostic criteria of hyperlipidemia: accord with any of the following: TC (> 6.22 mmol/L); 2.26 mmol/L (= TG (= 5.63 mmol/L); 2) LDL-C (> 4.14 mmol/L); 3) Accord with the diagnostic criteria of carotid atherosclerosis; 4) TCM syndrome differentiation belongs to phlegm stagnation syndrome; 5) Aged between 30 and 70 years; 6) The research program is approved and signed by the ethical committees of clinical research. The patient knows and voluntarily signs the informed consent; 7) Those who have stopped taking lipid-lowering drugs for more than 4 weeks or met the above criteria at the end of the introduction period.
Exclusion criteria
Exclusion criteria: 1) Pregnant or lactating women, allergic constitution and drug allergy; 2) Patients who have suffered from acute myocardial infarction, cerebrovascular accident, severe trauma or major surgery within six months; 3) Secondary hyperlipidemia; 4) Hyperlipidemia and homozygous hypercholesterolemia caused by drugs (phenothiazines, beta-blockers adrenocorticosteroids and some contraceptives, etc.); 5) Patients who are using heparin, thyroxine or other drugs that affect lipid metabolism, and those who have taken other lipid-lowering measures in the past two weeks; 6) Psychiatric patients with severe primary diseases such as liver, kidney and hematopoietic system.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TG;TC;LDL-C; | — |
Secondary
| Measure | Time frame |
|---|---|
| Integral of TCM Syndrome;HDL-C;Crouse; | — |
Countries
China
Contacts
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine