gout
Conditions
Interventions
Control group:Placebo
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Adult subjects with a diagnosis of gout and with TCM diagnosis of damp-heat obstruction syndrome; 2. Male and female patients aged 18-65 years with independent behavior ability; 3. Within 48 hours of acute attack, no other similar treatment was given within 14 days before the trial; 4. eGFR>=30ml/min/1.73m2; 5. Patients must sign informed consent to enter clinical research.
Exclusion criteria
Exclusion criteria: 1) Patients do not meet the above inclusion criteria; 2) Female patients during pregnancy or lactation; 3) Patients are allergic to drug allergy of this subject or individual hypersensitivity; 4) The level of ALT was higher than 2 times normal; 5) Patients with serious primary diseases such as heart, liver, kidney, brain, endocrine system,hematopoietic system or mental illness; 6) Patients with severe joint deformity or even labor loss ; 7) Patients received the same treatment within 2 weeks before the trial; 8) Patients have the poor compliance to difficult to complete the clinical observer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| interleukin-10;NACHT, LRR and PYD domains-containing protein 3;interleukin-6;Visual analog scale test;cysteinyl aspartate specific proteinase-1;Evaluation of joint tenderness;tumor necrosis factor-a;C-reactive protein;NF-?B;Ultrasound Imaging Score;Evaluation of joint swelling;Erythrocyte sedimentation rate;Evaluation of joint activity;blood uric acid;interleukin-1ß; | — |
Secondary
| Measure | Time frame |
|---|---|
| the total of urine uric acid in 24-hours;Serum xanthine oxidase;TCM syndrome curative effect ratings; | — |
Countries
China
Contacts
Public ContactGAO Jian-dong
TCM Institute of Kidney Disease, Shanghai university of Traditional Chinese Medicine
Outcome results
None listed