Clinical application of conservative rectal surgery after neoadjuvant therapy for low locally advanced rectal cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ITMCTR

Registry ID

ITMCTR1900002450

Enrollment

Unknown

Registered

2019-07-07

Start date

2020-01-01

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

low rectal cancer

Interventions

experimental group :Neoadjuvant Therapy + Rectal Conservative Surgery

control group:Neoadjuvant Therapy + Radical Surgery

Eligibility

Sex/Gender

All

Age

30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Those aged between 30 and 80 years; 2. ERUS, MR, CT and pathological biopsy were performed before operation, and the clinical staging was consistent with low locally advanced rectal cancer. 3. Agree to accept preoperative neoadjuvant therapy plus rectal conservative surgery.

Exclusion criteria

Exclusion criteria: Family history of colorectal cancer.

Design outcomes

Primary

Measure	Time frame
Distant metastasis rate within 2 years;5-year survival rate;Local recurrence rate within 2 years;	—

Secondary

Measure	Time frame
Ratio of R0 resection;Anal function;Oncological indicators;Urination functions;Incidence of complications;	—

Countries

China

Contacts

Public ContactZhu Yong

The Affiliated Nanjing Hospital of Nanjing University of Chinese Medicine

Zhuy839@163.com+86 15380881161

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026