Prehypertension
Conditions
Interventions
Sponsors
Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. With a systolic blood pressure in the range of 120 mm Hg to 139 mm Hg and/or a diastolic blood pressure in the range of 80 mm Hg to 89 mm Hg; 3. No western medicine or traditional Chinese medicine, acupuncture and moxibustion were used to control blood pressure (or the treatment was discontinued for 2 weeks); 4. Willing to be randomized to Tai Chi group or aerobic exercise group; 5. Ability to complete written questionnaires and operate electronic equipment independently; 6. Able to give informed consent.
Exclusion criteria
Exclusion criteria: 1. Secondary hypertension; 2. Pregnant and lactating women; 3. Non-dominant arm circumference > 50 cm; 4. Body mass index larger than 40.0 kg/m2; 5. Take benzodiazepines, antipsychotics or oral glucocorticoids (allowed to taken fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and escitalopram stably within 3 months); 6. Diagnosed with diabetes mellitus and coronary heart disease; 7. Chronic kidney disease with eGFR < 60 mL/min; 8. With known autonomic neuropathy (such as Shy-Drager syndrome, orthostatic hypotension, white coat hypertension); 9. Male's alcohol intake was more than 25 g/day or 140 g/week or female's alcohol intake was more than 15 g/day or 80 g/week; 10. Has played Tai Chi more than once a month in the past six months; 11. Vigorous sports activities more than three times a week; 12. Severe musculoskeletal problems lead to the inability to practise Tai Chi; 13. Current participants in clinical trials of other drugs or external therapies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| systolic blood pressure in office blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Four items of blood lipid;urinary microalbumin;Number of patients with office blood pressure changed to normal blood pressure (SBP<120 mmHg/DBP<80 mmHg);24-hour mean blood pressure;SCORE Score of European Clinical Practice;rapid blood glucose;urinary albumin;glycosylated hemoglobin;diastolic blood pressure in office blood pressure;24-hour ambulatory blood pressure variability;urine beta-2 microglobulin;Number of people with SBP 135-144 mmHg or DBP 85-89 mmHg in Home BP;Number of admissions due to acute cardio-cerebrovascular attacks and new atrial fibrillation events;6 months ± 7 days;Number of patients with office blood pressure changed to SBP140-159 mmHg/DBP90-99 mmHg; | — |
Countries
China
Contacts
Public ContactYanwei Xing
Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences
Outcome results
None listed