Ulcerative Colitis
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. patients with UC in the remission phase (determined by a UC Disease Activity Index score of 0–2 and bloody stool score of 0); the extent of UC is limited to left sided colitis and extensive colitis (Montreal classificati on E2, E3); the TCM syndrome was dampness stagnancy due to spleen deficiency syndrome; 2. men or women aged between 18 and 75 years; 3. participants voluntarily participated in this study, signed informed consent, and had good compliance.
Exclusion criteria
Exclusion criteria: 1. patients with active UC, severe UC, or acute fulminating type UC; 2. patients undergoing treatment with corticosteroids (oral, enemas, suppository, injectable solution); 3. patients treated with blood cell apheresis; 4. patients who were administered anti-tumor necrosis factor-a antibody within 90 days before starting the study drug; 5. patients with history of hypersensitivity to mesalazine and salicylic acid; 6. patients with serious cardiovascular disease, hemodyscrasia, or lung disease or with a history of these conditions; 7. patients with liver disease or kidney disease; 8. patients with malignant tumor as a complication; 9. pregnant women or those who were breastfeeding; 10. other conditions that the researcher don't consider it was suitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (diarrhea, abdominal pain, mucus stool, bloody purulent stool); | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM Syndrome Scale;The Short Inflammatory Bowel Disease Questionnaire (SIBDQ);The Short Health Scale (SHS);The Rating Form of IBD Patient Concerns (RFIPC); | — |
Countries
China
Contacts
Public ContactLiu Fengbin
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed