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Research for the nature of diabetes dampness syndrome based on intestinal microecological disorders and intestinal flora shift

Research for the nature of diabetes dampness syndrome based on intestinal microecological disorders and intestinal flora shift

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR1900002414
Enrollment
Unknown
Registered
2019-06-21
Start date
2019-07-01
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes

Interventions

Sponsors

Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Refer to the "Guidelines for the Prevention and Treatment of Type 2 Diabetes in China (2013 Edition)" Diagnostic criteria for type 2 diabetes: typical symptoms of diabetes (drinking, polyuria, polyphagia, weight loss) plus random blood glucose test =11.1 mmol/L or Plus fasting blood glucose test =7.0mmol / L or 2h after glucose load, blood glucose test = 11.1 mmol / L. In line with the damp-heat syndrome standard, the main symptoms: limb weight, head weight such as wrap, red tongue yellow greasy, sticky or constipation of stool, or uncomfortable after the stool; secondary symptoms: fullness of abdominal distension, nausea, not too much drink, The mouth has a stench and a slippery pulse. Emphasis is placed on "the yellow mossy" and "the head is trapped" and "the stool is abnormal."

Exclusion criteria

Exclusion criteria: Combined with severe heart, lung, liver and kidney diseases; combined with severe gastrointestinal diseases; history of intestinal surgery or trauma; pregnant or lactating; used expander, antidiarrheal, antispasmodic, in the past two weeks, Probiotics and antibiotics; long-term use of metformin, antibiotics or drugs that regulate intestinal flora.

Design outcomes

Primary

MeasureTime frame
IL-6;ROS;Serum insulin test;NF-kB;LPS;Oral saliva flora;Intestinal microbial metagenomics;Fasting blood sugar;RNS;Glycosylated hemoglobin;Blood lipid;IL-1ß;TLR4;TNF-?;Glycosylated serum protein;

Countries

China

Contacts

Public ContactLuo Huanhuan

Guangzhou University of Traditional Chinese Medicine

avenluo@gzucm.edu.cn+86 13826008227

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026