hydrocephalus after acute cerebral hemorrhage
Conditions
Interventions
Sponsors
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine (Sichuan Traditional Chinese Medicine Hospital)
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The first time onset cerebral hemorrhage; (2) Meet the diagnostic criteria for cerebral hemorrhage, and the GCS score is >4 points; (3) Aged 40 and 75 years old; (4) Agree to participate in the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) The patient's cerebral hemorrhage is caused by brain tumor, brain trauma, blood disease (secondary to anticoagulant and thrombolytic therapy); (2) with a mixed stroke or cerebral hemorrhage with severe bleeding needs to surgery; (3) The clinical manifestations of cerebral palsy, including the disappearance of ipsilateral pupillary reflexes and other third pairs of cranial nerve paralysis; (4) with pulmonary heart disease, unstable angina or acute myocardial infarction within 6 months; (5) with neurological deficits (mRS>2) before the onset of AICH; (6) Accompanied by severe cardiac insufficiency (NYHA cardiac function classification III-IV); (7) Accompanied by severe hepatic insufficiency (the liver function test results exceed 2 times the upper limit of the normal range); (8) Accompanied by severe renal insufficiency (the serum creatinine is more than twice the upper limit of the normal range); (9) Active gastrointestinal bleeding occurs after the onset of AICH in patients; (10) The patient has a heavier blood system or other systemic underlying disease; (11) The patient is in a state of pregnancy or breastfeeding, or has a severe allergic disease or is allergic to multiple drugs; (12) The patient has other diseases that cause his neurological deficit, or join the study to aggravate his condition; (13) The patient has participated in other clinical trials in the past 3 months; (14) Patients without malignant tumors and receiving radiotherapy and chemotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematoma volume;NIHSS score;The incidence of hydrocephalus after acute cerebral hemorrhage in two cohorts;Hematoma volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| The occurrence of death endpoints in each study cohort from the implementation of the program to the end of treatment;Quality of life indicator; | — |
Countries
China
Contacts
Public ContactLu Yun
Hospital of Chengdu University of Traditional Chinese Medicine
Outcome results
None listed