ulcerative colitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for normal volunteers: 1) normal healthy without any previous medical history; 2) the defecation law is unobstructed and the fecal material is soft forming; 3) persons aged between 18 and 65 years; 4) good compliance with researchers' observation, voluntary participation, and signing of informed consent. Ulcerative colitis group inclusion criteria: 1) those with clinical symptoms, colonoscopy and intestinal mucosa biopsy pathological specimens meeting the diagnostic criteria at the same time; 2) persons aged between 18 and 65 years; 3) the activity score of ulcerative colitis evaluated by the modified Mayo scoring system is less than or equal to 10 points; 4) good compliance with researchers' observation, voluntary participation, and signing of informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria for normal volunteers: 1) those who do not meet the inclusion criteria; 2) pregnant or lactating women with allergies. Ulcerative colitis group exclusion criteria: 1) clinical symptoms, colonoscopy findings, or pathological specimens of intestinal mucosa biopsy fail to meet the diagnostic criteria; 2) pregnant or lactating women, allergic constitution and allergic to the observed drugs; 3) patients with severe primary diseases of cardiovascular, cerebrovascular, liver, kidney and hematopoietic system; 4) patients with intestinal stenosis, intestinal obstruction, intestinal perforation, rectal polyps, toxic colonic dilatation, colon cancer, rectal cancer and anal diseases;Acute fulminant, severe patients; 5) the patient fails to use the medicine as prescribed, and the efficacy cannot be judged or the efficacy is affected by incomplete data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intestinal flora;Enteric Virome;DAI; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of T.C.M