Ulcerative colitis
Conditions
Interventions
Sponsors
Jiangsu Province Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis is in line with the active period of ulcerative colitis; 2. According to the improved Mayo score standard, the condition is mild (score 3-5 points); 3. Differentiation of TCM syndrome is heat-dampness and stasis blocked accompanied with spleen and stomach weakness; 4. 18 to 65 years old; 5. Those who participate in this clinical study voluntarily, and have signed informed consent already.
Exclusion criteria
Exclusion criteria: 1. Patients during remission period, moderate and severe active periods; 2. Pregnancy, lactation, or birth planning recent ; 3. Severe allergy tendency and those who allergies to the known ingredients of mesalazine or Hudi Changrong capsules; 4. Combined with severe cardiovascular and cerebrovascular diseases (chronic heart failure, cardiac function is level III or above according to New York grading standard, severe arrhythmia, severe stroke sequelae). Liver, kidney and hematopoietic system has serious primary diseases, including blood ALT, AST and Cr over the normal upper limit; 5. Ulcerative colitis companied with serious complications, such as local stenosis, intestinal obstruction, intestinal perforation, multiple polyps in the intestine, toxic megacolon, rectal cancer, etc. 6. Patients with mental disorders and mental disorders; 7. Patients who have participated in other meidical clinical studies in the past 3 months; 8. In addition to mesalazine, patients are receiving other treatments for ulcerative colitis; 9. Seriously conditions which need to be carried on urgent treatments; 10. It is not appropriate to participate in this clinical research judged by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical remission rate;Clinical effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mucosal healing rate;Single symptom score;TCM syndrome score;Quality of life score;Endoscopic response rate; | — |
Countries
China
Contacts
Public ContactDong Yun
Science and Technology Department, Jiangsu Province Hospital of Chinese Medicine
Outcome results
None listed