Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Repeated knee joint pain in the past month; 2. X-ray films (standing position or load-bearing position) showed narrowing of joint space, subcartilage osteosclerosis and / or cystic degeneration, and formation of osteophyte at the edge of the joint; 3. Aged = 50 years old; 4. Morning stiffness time = 30 min; 5. There is bone friction sound (feeling) during the activity.
Exclusion criteria
Exclusion criteria: 1. There is skin damage around the knee joint; 2. Patients with history of knee surgery and severe trauma; 3. Patients with secondary OA, complicated with rheumatoid arthritis, gouty arthritis, infectious arthritis and other joint diseases; 4. Patients with diabetes, systemic infection, severe abnormal liver and kidney function, malignant tumor and other diseases; 5. Patients received NSAIDs, intra-articular injection and other related treatment in the past 3 months; 6. Those who are allergic to the drugs in this study; 7. Pregnant or lactating women; 8. Mental disorder or cognitive dysfunction; 9. Those who did not accept or could not adhere to the treatment plan of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;Womac score; | — |
Countries
China
Contacts
Guanghua Hospital, Shanghai University of Chinese Medicine