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Clinical analgesic effect and Mechanism of Massage manipulation in the treatment of knee Osteoarthritis

Clinical analgesic effect and Mechanism of Massage manipulation in the treatment of knee Osteoarthritis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR1900002311
Enrollment
Unknown
Registered
2019-05-02
Start date
2019-05-10
Completion date
Unknown
Last updated
2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Sponsors

Guanghua Hospital, Shanghai University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Repeated knee joint pain in the past 1 month; (2)X-ray films (standing position or load-bearing position) showed narrowing of joint space, subcartilage osteosclerosis and / or cystic degeneration, and formation of osteophyte at the edge of the joint; (3) Age = 50 years; (4) Morning stiffness time = 30 min; (5) there is bone friction sound (feeling) during the activity. Osteoarthritis of knee joint can be diagnosed by meeting the diagnostic criteria of 1 + (any 2 of 2, 3, 4 and 5).

Exclusion criteria

Exclusion criteria: (1) there was skin damage around the knee joint; (2) patients with history of knee surgery and severe trauma; (3) patients with secondary OA, complicated with rheumatoid arthritis, gouty arthritis, infectious arthritis and other joint diseases; (4) patients with diabetes mellitus, systemic infection, severe abnormal liver and kidney function, malignant tumor and other diseases; (5) the patients were treated with non-steroidal anti-inflammatory drugs and intra-articular injection in the past 3 months; (6) those who were allergic to drugs in this study; (7) pregnant or lactating women; (8) patients with mental disorder or cognitive dysfunction; (9) those who did not accept or could not adhere to the treatment plan of this study.

Design outcomes

Primary

MeasureTime frame
PPT;Chinese version of pain self-efficacy questionnaire;Pain visual analog score;

Countries

China

Contacts

Public ContactXu Hui

Guanghua Hospital, Shanghai University of Chinese Medicine

1511911882@qq.comv+86 15036065035

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026