A randomized controlled study for the treatment of depression by regulating circadian rhythm with Sini San

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ITMCTR

Registry ID

ITMCTR1900002301

Enrollment

Unknown

Registered

2019-04-23

Start date

2019-05-08

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

western drugs group:paroxetine

chinese and western combined drugs group:Sini San combined with paroxetine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)Meet diagnostic criteria; (2)Physical examination and related laboratory examination exclude depression caused by physical diseases; (3)Average time in bed at night is 7 hours; (4)Patients voluntarily participate in clinical trials and sign the informed consent; (5)Aged 18 to 65 years; (6)Junior high school education or above.

Exclusion criteria

Exclusion criteria: (1)Concomitant physical disease or brain organic disease; (2)Have used or are using any antidepressant or antipsychotic drugs in the past two weeks; (3)Remove emotional disorders caused by life factors such as alcohol or coffee, strong tea; (4)Women during pregnancy, lactation and menstruation; (5)Participating in other clinical trials within one month; (6)Suicidal.

Design outcomes

Primary

Measure	Time frame
Hamilton Depression Scale,HAMD;Dark melatonin;PAD;	—

Countries

China

Contacts

Public ContactChen Jun

Shaanxi Traditional Chinese Medicine Hospital

chj2002819@163.com+86 15991658129

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026