Multiple System Atrophy
Conditions
Interventions
Control Group:Western medicine
Sponsors
Dongfang Hospital of Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Healthy persons with age and sex matched with MSA patients; 2. Probable MSA patients and Possible MSA patients (in accordance with Second consensus statement on the diagnosis of multiple system atrophy 2008); 3. Aged 30 to 80 years.
Exclusion criteria
Exclusion criteria: 1. Have a similar family history; 2. The existence of Multiple System Atrophy characteristics due to systemic diseases or other clear causes; 3. Hallucinations unrelated to the drug; 4. Neurological examination shows the standard of dementia in accordance with the 4th edition (Dsm-?) of the Diagnostic and Statistical Manual for Mental Disorders in the United States; 5. Apparent slow or vertical nuclear gaze paralysis of the vertical rapid scan; 6. Evidence of local cerebral cortex damage, such as aphasia, ectopic limb disorder, parietal dysfunction, etc.; 7. Pregnant women, with severe heart, liver and kidney and other diseases can not complete the scale and related examination of the person.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MSA-NMSS;UMSARS;fMRI(BOLD\DTI); | — |
Secondary
| Measure | Time frame |
|---|---|
| MoCA;time of nocturnal urination;HAMD-21;postural hypotension value;HAMA-14;frequency of urinary incontinence; | — |
Countries
China
Contacts
Public ContactChen Zhigang
Outcome results
None listed