Hospital-acquired pneumonia with multi-drug resistant organism
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Complying with the diagnostic criteria of Western Medicine; (2) Pathogenic diagnosis conforms to MDRO criteria; (3) Aged 40-85 years; (4) Signing informed consent.
Exclusion criteria
Exclusion criteria: (1) Having serious heart, brain, liver, kidney and other primary diseases or malignant tumors, systemic diseases and other diseases in the acute or progressive stage; (2) with a history of operation within two months, accompanied by infection of the surgical site; (3) Death within 72 hours after admission; (4) Psychiatric patients and pregnant women; (5) active pulmonary tuberculosis; (6) those who have a history of allergy to medicines in treatment; (7) Recent drug and alcohol abuse; (8) Those who failed to respond to other antibiotics or other drugs three months before the drug clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory factor level;clinical pulmonary infection score;Removal rate of drug-resistant pathogens; | — |
Secondary
| Measure | Time frame |
|---|---|
| Integral of TCM Syndrome;Assessment of severity of illness;Hospitalization Days;mortality rate;successful rate of weaning from mechanical ventilation;Mechanical ventilation time;Pulmonary CT Imaging; | — |
Countries
China
Contacts
LongHua Hospital Shanghai University of Traditional Chinese Medicine