Topic: Stroke Research Network
Conditions
Interventions
Motor training:
We will study how patients can learn to improve their performance in three different movements that are important for fine hand function: wrist extension (needed for grasping and relea
Sponsors
University College London Hospitals NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. First ever ischaemic stroke (previous transient ischaemic attack [TIA] is not a problem) 2. One to three months post stroke 3. Some movement in the wrist and fingers (wrist extension greater than or equal to 20° and thumb flexion greater than or equal to 10°) 4. English speaking 5. Aged over 18 years of age, either sex
Exclusion criteria
Exclusion criteria: 1. Intracerebral or subarachnoid haemorrhage 2. Large strokes (greater than 50% of the middle cerebral artery [MCA] territory) 3. Increased muscular tone (greater than 2 in the Ashworth scale or not able to let go after grip without using the intact hand) 4. Cardiac pacemaker or intracardiac lines 5. Metallic objects in the head or in the eyes (e.g. clips from surgery, exposure to fast metallic flakes; metal in the mouth/teeth is not a problem) 6. Any history of epilepsy or fits including childhood 7. Inability to consent or comply with the study procedures (cognitive impairment, significant aphasia, visual field defect, or non-English speakers)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor performance, collected during each practice | — |
Secondary
| Measure | Time frame |
|---|---|
| Standardised tests of the arm and hand function that have been used repeatedly to assess recovery, performed on day 1 and 5: 1. Action Research Arm Test (ARAT) 2. Jebsen Taylor Hand Test 3. 9-Hole Peg Test 4. Electrophysiological measures of corticospinal excitability determined by TMS | — |
Countries
United Kingdom
Outcome results
None listed