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Genomics to combat Resistance against Antibiotics for Community acquired lower respiratory tract infection (LRTI) in Europe: INternet Training for Reducing antibiOtic use trial

Genomics to combat Resistance against Antibiotics for Community acquired lower respiratory tract infection (LRTI) in Europe: INternet Training for Reducing antibiOtic use - a multicentre randomised interventional process of care trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN99871214
Enrollment
19600
Registered
2010-07-07
Start date
2010-10-01
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Primary Care Research Network for England

Interventions

GP practices will be randomised into 4 intervention groups: 1. Routine care 2. Routine care plus GP training into optimal antibiotic use and patient education with book

Sponsors

University of Southampton (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years and over, either sex 2. An illness where a acute cough or worsened cough is the main or dominant symptom, or a clinial presentation suggesting LTRI, greater than or equal to 28 days duration 3. First consultation for this illness episode 4. Seen within normal consulting hours 5. First time in this study 6. Ability to fill out study materials 7. Written consent to participate 8. Immunocompetent

Exclusion criteria

Exclusion criteria: Patients who are unable to properly consent or fill out the diary (dementia, psychosis, severe depression)

Design outcomes

Primary

MeasureTime frame
Antibiotic prescribing, measured at baseline and after intervention

Secondary

MeasureTime frame
1. Patient complications after the interventions by measuring significant deterioration of illness 2. Cost effectiveness of the interventions by measuring resource use 3. Issues behind the successes, difficulties and limitations of implementing behaviour change using GP focus groups 4. Patient perceptions of the process using patient interviews

Countries

Belgium, Netherlands, Poland, Spain, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 23, 2026