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Right heart function in patients with arrhythmogenic right ventricular cardiomyopathy

Quantitative CMR analysis of right ventricular function and synchronicity in patients with arrhythmogenic right ventricular cardiomyopathy: Could this be predictive of arrhythmias

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN99714144
Enrollment
60
Registered
2017-03-17
Start date
2009-10-30
Completion date
Unknown
Last updated
2022-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arrhythmogenic right ventricular cardiomyopathy (ARVC) Circulatory System Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Interventions

Participants (both healthy controls and those with ARVC) undergo a cardiac magnetic resonance imaging (CMR). This is done for participants as part of their clinical workup for an ARVC diagnosis (accor

Sponsors

Linköping University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients: 1. Diagnosis of a definite ARVC 2. Have not received an implantable cardioverter defibrillator (ICD) 3. Aged 18 years and older Healthy Participants: 1. Age matched asymptomatic who lack a family history of premature cardiovascular disease 2. Not on cardiac medication 3. Pass a cardiac exercise test 4. Aged 18 years and older

Exclusion criteria

Exclusion criteria: The presence of an implantable cardioverter defibrillator (ICD).

Design outcomes

Primary

MeasureTime frame
1. Strain values are measured using Feature tracking method once with clinically indicated CMR with additional acquisition model at baseline 2. Time to peak strain is measured using the Feature tracking method with clinically indicated CMR with additional acquisition model at baseline

Secondary

MeasureTime frame
Arrhythmia relation to strain values are measuring using the CMR examination with additional acquisition and the yearly interrogation of ICDs and available Holter recordings at year one, two, three, four and five (or when clinically necessary)

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026