Epidural-related maternal fever in active labour Pregnancy and Childbirth Pyrexia during labour, not elsewhere classified
Conditions
Interventions
Women are enrolled either in antenatal clinic or on admission to labour ward. A single blood sample is obtained around the time of epidural insertion. Clinical outcomes are collected for the duration
Sponsors
Queen Mary University of London
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Aged =18 years old 2. Singleton or twin pregnancy 3. Any gestational age 4. Requesting an epidural for labour analgesia
Exclusion criteria
Exclusion criteria: 1. Unwilling or unable to give consent 2. Refusal of consent for competent participants 3. Inability to understand written and/ or verbal English 4. Immune/genetic syndromes/mutations 5. Microbiologically proven infection prior to epidural insertion 6. Established pyrexia 7. Intrauterine death
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of one or both of the following: 1. Maternal temperature >38°C (triggered by RCOG guidelines for two temperatures >37.5°C) recorded as part of their standard care from patient notes at least 4h after epidural analgesia is commenced 2. Prescription of antibiotics during labour before delivery measured from patient notes before delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical outcomes for mother and baby measured from patient notes during their hospital stay | — |
Countries
England, United Kingdom
Outcome results
None listed