Postprandial glycaemic control Nutritional, Metabolic, Endocrine Postprandial glycaemic control
Conditions
Interventions
The trial has a randomised crossover design and so each subject would act as their own control. Randomisation sequence was generated using www.randomization.com using the randomly permuted blocks met
Sponsors
Phynova Group Limited
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Consent to study protocol 2. Aged 18-60 years 3. BMI 20-29.9 kg/m² 4. Fasting blood glucose <6.1 mmol/l
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating 2. Any known food allergies or intolerance to mulberry leaf extracts 3. Presence of a medical condition, or taking medication known to affect glucose regulation and/or influence digestion and absorption of nutrients 4. History of diabetes mellitus (type I or type II), or the use of antihyperglycaemic drugs or insulin to treat diabetes or related conditions 5. Use of steroids, protease inhibitors, or antipsychotics which would affect glucose metabolism and body fat distribution
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incremental area under curve for plasma glucose concentration over 120 min, plasma glucose concentration collected by fingerprick blood sample at 0, 15, 30, 45, 60, 90, and 120 min | — |
Secondary
| Measure | Time frame |
|---|---|
| Incremental area under curve for plasma insulin concentration over 120 min, plasma insulin concentration collected by fingerprick blood sample at 0, 15, 30, 45, 60, 90, and 120 min | — |
Countries
United Kingdom
Outcome results
None listed