Post operative intraperitoneal adhesions Surgery Post operative intraperitoneal adhesions
Conditions
Interventions
On completion of the first surgical procedure for each subject, the peritoneum was cleansed and irrigated with saline. A single dose of pumactant powder 240 mg (comprising of 3 puffer devices administ
Sponsors
Research and Innovation Service, University of Dundee (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female subjects ( > 18 years old) were recruited into the study if it was thought that at the primary surgical procedure, they required the formation of a temporary stoma 2. Patients undergoing emergency treatment of obstructed /perforated carcinoma of the bowel or colonic diverticulitis by Hartmanns procedure 3. Patients undergoing elective low anterior bowel resection for the treatment of rectal carcinoma requiring formation of a temporary ileostomy
Exclusion criteria
Exclusion criteria: 1. Patients unable to comply with the study requirements, had cognitive impairments, had a history of drug and / or alcohol abuse 2. Patients receiving steroid medication 3. Patients had metastatic disease 4. Patients had American Society of Anesthesiologists (ASA) fitness grade of IV or above 5. Pregnant or lactating females
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The evaluation of the efficacy of pumactant 240 mg in reducing the formation of peritoneal adhesions following abdominal surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the safety and tolerability of pumactant 240 mg used in the peritoneal cavity following abdominal surgery | — |
Countries
United Kingdom
Outcome results
None listed