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High blood pressure control and lipid lowering in patients at high cardiovascular risk: a cluster randomised factorial comparison of educational and protocol-based interventions to help primary care teams improve control of patients with poor risk factor control

High blood pressure control and lipid lowering in patients at high cardiovascular risk: a cluster randomised factorial comparison of educational and protocol-based interventions to help primary care teams improve control of patients with poor risk factor control

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN99472145
Enrollment
10000
Registered
2010-06-18
Start date
2006-06-01
Completion date
Unknown
Last updated
2017-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Cardiovascular, Diabetes Research Network, Primary Care Research Network for England

Interventions

1. Case management 2. Protocol-based treatment suggestions 3. Clinical educational support 4. Expertise sharing Follow-up length: 12 months

Sponsors

William Harvey Research Institute (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Elevated systolic blood pressure greater than or equal to 160 mmHg within the last 12 months 2. Elevated total cholesterol greater than or equal to 5 mmol/l 3. Patients in secondary prevention, or risk equivalent, or hypertensives in primary prevention at more than 20% 10-year cardiovascular disease (CVD) risk by QRISK2 or Framingham equations 4. Male and female, lower age limit of 40 years

Exclusion criteria

Exclusion criteria: Compelling reasons to avoid increase in blood pressure or lipid-lowering medication, such as severe debilitating illness or terminal cancer

Design outcomes

Primary

MeasureTime frame
Change in blood pressure (BP) treatment at 1 year

Secondary

MeasureTime frame
1. Change in lipid treatment at 1 year 2. Change in systolic blood pressure (BP) at 1 year 3. Change in total cholesterol at 1 year

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026