Apical lesions of permanent upper incisors Oral Health
Conditions
Interventions
Following the randomization procedure, patients will be divided into two groups (45 permanent upper incisors in each group) using the simple randomization method and a random sequence created using th
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy patients without any systemic disease or compromised immune status 2. Patients aged between 25 and 44 years old 3. Patients with at least one permanent closed-apex upper incisor first with an asymptomatic apical lesion sized 5 to 10 mm²
Exclusion criteria
Exclusion criteria: 1. Patients with advanced periodontitis (more than 5 mm periodontal attachment and bone loss) 2. Untreatable teeth (root fracture, unrestorable tooth, massive internal or external resorption) 3. Smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Postoperative pain measured using the visual analog scale (VAS) before treatment, 1, 3, 7 and 14 days 2. Swelling and tooth mobility measured according to their presence/absence before treatment, 1, 3, 7 and 14 days 3. Apical lesion volume and density measured using CBCT images before treatment, 6, and 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of apical lesions healing measured using CBCT images by comparing the baseline with 6, and 12 months follow-up images | — |
Countries
Syria
Outcome results
None listed