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The utilization of a mixture containing platelet-rich fibrin and Synthetic Hydroxyapatite (Nanobone) substance in the process of enhancing the volume of the maxillary sinus for medical purposes.

Clinical application of platelet-rich fibrin mixed with Synthetic Hydroxyapatite (Nanobone) material in maxillary sinus augmentation - randomised clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN99349253
Enrollment
50
Registered
2024-03-18
Start date
2023-07-15
Completion date
Unknown
Last updated
2024-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reduced bone height in the posterior maxilla (1-4 mm) Oral Health

Interventions

Participants will be randomized to test or control treatment lateral window technique for sinus augmentation using Liquid PRF with Nanobone / Nanobone alone based on computer-generated random codes. T

Sponsors

SUAVEMED
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. At least eighteen years old 2. Have healed edentulous sites on the posterior maxillae region with 5mm or less residual bone height to place implants in need of sinus graft procedure.

Exclusion criteria

Exclusion criteria: 1. Alcoholism 2. Smoking 3. Drug abuse 4. Diabetes 5. Heart disease 6. Bleeding disorders 7. Weakened immune systems 8. Radiation exposure 9. Bleeding disorders 10. Past or ongoing use of steroids or bisphosphonates 11. Prior bone augmentation

Design outcomes

Primary

MeasureTime frame
Pain perception measured using the Visual Analogue Scale during the first week after surgery

Secondary

MeasureTime frame
1. Quality of life measured using the Oral Health Impact Profile 14 translated in Portuguese during the first week after surgery 2. Implant osseointegration success rate measured using clinical examination at 6 months after surgery 3. Patient registration of analgesic medication usage during the first week after surgery

Countries

Portugal

Contacts

Public ContactMarco ;Rosana Infante da Câmara ;Costa

;

m_infante2@hotmail.com;rosana_gcosta@hotmail.com+351914112775;+351 914240555

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026