Anti-microbial varnish in the management of root caries in mentally and/or medically compromised older adults

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN99286964

Enrollment

150

Registered

2004-01-23

Start date

1997-04-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root caries Oral Health Dental caries

Interventions

1. Use of antimicrobial varnish containing chlorhexidine and thymol in conjunction with a remineralising, fluoride-containing varnish on clinical and microbiological parameters of root carious lesions

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. 150 elderly frail patients 2. Minimum of four teeth 3. At least one root caries lesion 4. Amenable to dental examination 5. Expected to survive the length of the study

Exclusion criteria

Exclusion criteria: Antibiotics less than four weeks ago.

Design outcomes

Primary

Measure	Time frame
1. Effect on the salivary flora 2. Changes in clinical status 3. Dimensions of root lesions	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026