Pediatric patients with pneumonia Respiratory
Conditions
Interventions
Children will be randomly assigned to one of two groups in a 1:1 ratio. The intervention group will receive standard antibiotic treatment plus oral probiotics. The control group will receive standard
Sponsors
Hung Yen Provincial People’s Committee
Hung Yen Provincial Department of Science and Technology
Thai Binh Pediatrics Hospital
Eligibility
Sex/Gender
All
Age
2 Months to 16 Years
Inclusion criteria
Inclusion criteria: 1. A confirmed diagnosis of pneumonia at any severity level. 2. CRP testing performed to determine the indication for antibiotic therapy according to the study protocol. Only children with CRP =30 mg/dL were eligible for inclusion. 3. Written informed consent obtained from the family after full explanation of the study objectives, potential benefits, risks, and participants’ rights; consent signed by a parent or legal caregiver.
Exclusion criteria
Exclusion criteria: 1. Contraindications to probiotics, including allergy or hypersensitivity to any component of the probiotic preparation. 2. Severe immunodeficiency or congenital immunological disorders. 3. Use of probiotics, probiotic supplements, or products with similar components prior to hospital admission, which may confound the assessment of the intervention’s effectiveness. 4. Presence of severe underlying conditions or the need for special treatment regimens, such as: cancer receiving chemotherapy or radiotherapy, hepatic failure, advanced renal failure, severe cyanotic congenital heart disease requiring surgery, or other life-threatening conditions requiring intensive care. 5. Inability to ensure complete in-hospital follow-up, for example: likelihood of early referral, transfer to another facility, or discharge within 48 hours of admission. 6. Lack of cooperation with necessary procedures for treatment evaluation, such as blood sampling for laboratory tests.
Countries
Viet Nam
Contacts
Public ContactTrong Kiem Tran
Outcome results
None listed