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Effect of Hydrocortisone Treatment modality on Glycemic Control in patients with Septic Shock

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN98820688
Enrollment
48
Registered
2006-10-18
Start date
2005-07-05
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vasopressor-dependent septic shock Signs and Symptoms Septic shock

Interventions

Septic shock patients who are considered to benefit from the corticosteroid treatment are randomly assigned to receive hydrocortisone either by bolus treament or by continuous infusion with equivalent

Sponsors

Päijät-Häme Central Hospital (Finland)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Septic shock patients meeting the criteria for septic shock according to the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference.

Exclusion criteria

Exclusion criteria: 1. Patients under 18 years of age 2. Patients with diabetes 3. Patients receiving glucocorticoids

Design outcomes

Primary

MeasureTime frame
Mean blood glucose levels in study groups and the number of hyperglycemic (more than 7 mmol/l) and hypoglycemic (less than 3 mmol/l) episodes.

Secondary

MeasureTime frame
Shock reversal during the five day study period and the amount of nursing workload needed to maintain normoglycemia.

Countries

Finland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026