Clinical and molecular mechanisms of periodontal wound healing following surgical treatment of localised aggressive periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN98564858

Enrollment

Registered

2005-09-30

Start date

2005-01-12

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis Oral Health Periodontitis

Interventions

1. Group A: regeneration treatment 2. Group B: repair treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Not provided at time of registration

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
The main clinical outcome variables will be Lifetime Cumulative Attachment Loss (LCAL) and level of bone loss. The main laboratory outcome variables will be change in level of specific growth factors (Platelet-Derived Growth Factor [PDGF], Vascular Endothelial Growth Factor [VEGF], Transforming Growth Factor beta [TGFb]), Bone Morphogenetic Protein [BMP] and osteoprotegerin.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026