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Effect of miswak-black silica toothbrush on the color stability and surface roughness of resin composite, resin-modified glass ionomer, and enamel surface, and its remineralization potential: an in vitro and in vivo study

Effect of miswak-black silica toothbrush on the color stability and surface roughness of resin composite, resin-modified glass ionomer, and enamel surface, and its remineralization potential: an in vitro and in vivo study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN98560812
Enrollment
50
Registered
2025-10-31
Start date
2025-10-20
Completion date
Unknown
Last updated
2026-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antibacterial effect, surface roughness and color stability of enamel, resin composite, and resin-modified glass ionomer Oral Health

Interventions

Group 1: Miswak-Black Silica toothbrush (Shinyei Kaisha, Japan) used twice daily for 2 minutes without toothpaste for 1 week. Group 2: Colgate soft manual toothbrush used with fluoride toothpaste twic

Sponsors

Taibah University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Adults aged 18–35 years 2. Brushes teeth twice daily 3. Plaque index =2

Exclusion criteria

Exclusion criteria: 1. Open carious lesions 2. Plaque index >2 3. Severe gingivitis (score >2) 4. Throat infection 5. Irregular brushing habits 6. Smoking 7. Medically compromised condition

Design outcomes

Primary

MeasureTime frame
Bacterial colony-forming units (CFUs) on toothbrush bristles after 48-hour incubation (Streptococcus mutans)—

Secondary

MeasureTime frame
1. Mean surface roughness change (?Ra) measured with a 3D profilometer before and after brushing simulation 2. Color variation (?E00) measured with a Vita Easyshade III spectrophotometer before and after brushing 3. Enamel remineralization examined via scanning electron microscopy (SEM) following demineralization and brushing simulation—

Countries

Saudi Arabia

Contacts

Public ContactAnfal Alqussier
aalqusayr@taibahu.edu.sa+966 (0)556622191

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 23, 2026