Optimisation of vitamin A dosing schedules in infancy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN98554309

Enrollment

220

Registered

2005-10-10

Start date

2001-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin A deficiency Nutritional, Metabolic, Endocrine Vitamin A supplementation

Interventions

Early high dose Vitamin A schedule versus standard WHO schedule.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Consenting mothers and new born infants in six villages in the West Kiang region of The Gambia.

Exclusion criteria

Exclusion criteria: 1. Congenital defects 2. Birthweight under 2200 g

Design outcomes

Primary

Measure	Time frame
1. Vitamin A status in mothers and infants 2. Heliobacter pylori infection in infants 3. Nasopharyngeal pneumococcal carriage in mothers and infants 4. Gut permeability in infants assessed by Dual Pugar Permeability Test (DSPT)	—

Secondary

Measure	Time frame
1. Infant growth 2. Infant morbidity 3. Breast milk sodium-potassium ratios 4. Breast-milk oligosaccharides	—

Countries

Gambia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026