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Feasibility RCT: In-MINDD Profiler & Supportive Environment

Innovative Midlife Intervention for Dementia Deterrence (In-MINDD) feasibility randomised controlled trial in four European primary care settings

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN98553005
Enrollment
600
Registered
2014-05-07
Start date
2014-07-01
Completion date
Unknown
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia Mental and Behavioural Disorders Demetia

Interventions

In-MINDD arm of trial. Participants in the In-MINDD arm will receive a letter telling them that they have been allocated to the In-MINDD arm of the trial and they should contact their
or taking up a new activity, such as learning a language. Participants will be able to access advice and support about these activities from the In-MINDD online system. At three months, participants w
for how long
and what sites they visit. After six months participants will meet with the researcher or practice nurse again and update their information on the In-MINDD system in order to generat

Sponsors

NHS Greater Glasgow and Clyde (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Registered with a participating practice 2. Age 40 ? 60 on date of consent 3. Presence of any one (or more) of the following risk factors 3.1. Depression ? previous history OR active episode of minor depression as recorded on medical record ? IF GP deems patient fit to participate 3.2. Diabetes (diagnosis e.g. on a diabetes disease register) 3.3. Hypertension (as per national guidelines) 3.4. Obesity (BMI of 30.0 or above) 3.5. Current smoker 3.6. High cholesterol (as per national guidelines) 3.7. Coronary heart disease (diagnosis e.g. on a CHD disease register) 3.8. Self reported sedentary lifestyle 3.9. Self reported lack of cognitive stimulation 4. Medically stable 5. Literate in language of the partner country where patient is recruited (English/Dutch/French as appropriate). 6. Access to the internet in order to communicate by email and access information online

Exclusion criteria

Exclusion criteria: 1. Active episode of major depression, if GP deems patient too severely ill to participate, recorded in medical record or assessed using a validated assessment score e.g. HADS 2. People who are unable to give informed consent 3. People who have dementia

Design outcomes

Primary

MeasureTime frame
Global risk score, calculated on the basis of a basket of individual risk factors identified from work package 1 of In-MINDD. These will include physical and cognitive activity; presence of depression, diabetes and/or cardiovascular disease; high cholesterol; smoking status; hypertension; and obesity. dementia risk score will be measured by a dementia risk questionnaire. The questionnaire will be completed at baseline and at study completion (six months) and will be comprised of information on participants' mood, physical activity, cognitive activity and diet via four validated instruments which have been carefully selected and adapted where necessary.

Secondary

MeasureTime frame
Changes in individual risk factors

Countries

France, Ireland, Netherlands, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 15, 2026