Does remote ischaemic preconditioning reduce heart and cerebral damage following carotid endarterectomy? A randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN98544942

Enrollment

Registered

2006-01-13

Start date

2006-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid stenosis Circulatory System Carotid Stenosis

Interventions

Patients randomised to undergo ischaemic preconditioning will have a thigh cuff inflated on one leg until flow in the pedal arteries disappears. After five minutes have elapsed, the cuff will be move

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing elective carotid endarterectomy.

Exclusion criteria

Exclusion criteria: 1. Patients with an ankle-brachial pressure index less than 0.7 2. Patients who have undergone previous lower limb amputation 3. Blind patients

Design outcomes

Primary

Measure	Time frame
Primary neurological outcome: proportion of patients developing a significant change in saccadic latency as determined by quantitative oculometry. Cardiac outcome: serial troponin I levels post-operatively.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026