Need for dental implant placement to replace missing tooth/teeth Oral Health
Conditions
Interventions
The aim of this exploratory randomized, controlled clinical trial is to assess the effect of one-piece individualized titanium abutments on biomarkers associated with inflammation and tissue degradati
Sponsors
Medical University of Vienna
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged >18 years old 2. One or more missing teeth in the molar region of the upper and/or lower jaw 3. Adequate bone quality and availability for implant placement 4. No signs of inflammation in the region where implant placement is planned 5. Good systemic health conditions 6. Stable occlusion 7. Willing to participate and attend follow-up appointments
Exclusion criteria
Exclusion criteria: 1. Presence of untreated periodontitis 2. Smokers (>10 cigarettes per day) 3. Alcoholism or drug abuse, history of chemotherapy or radiation 4. Diabetes with >7.5 HbA1c
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peri-implant inflammation and tissue destruction measured by levels of biomarkers (pg/ml) in peri-implant crevicular fluid (PICF) at suture removal, at crown delivery and at 6 months follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Marginal bone loss (mm) measured radiographically at suture removal, at crown delivery and at 6 months follow-up | — |
Countries
Austria
Outcome results
None listed