Topic: Generic Health Relevance and Cross Cutting Themes
Conditions
Interventions
All patients volunteering for this study will undergo conventional XR fluoroscopy as per standard care, followed by an additional MRI examination. Data collection involves completion of demographic pr
Sponsors
Cambridge University Hospitals NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. All children (usually boys) between the ages of 0 and 3 years referred for direct micturating cysto-urethrography (MCUG) 2. All children with hydronephrosis diagnosed antenatally on foetal ultrasound 3. Age range: 0 days - 3 years, male and female
Exclusion criteria
Exclusion criteria: 1. Usual MR exclusion criteria will apply, but are highly unlikely in this age group. The include pregnancy, claustrophobia, cardiac pacemakers, metallic implants, cardiac defibrillator implants, aneurysm clips or metallic heart valves, and cochlear or inner ear implants. These exclusion criteria clearly apply to all people within the vicinity of the MRI scanner, and therefore apply equally to the parents/guardians in this study. 2. Previous reaction to the relevant x-ray or MRI contrast medium (including gadolinium) 3. Congenital abnormalities that make X-ray fluoroscopy of MR fluoroscopy impractical
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ability of the MR fluoroscopy examination to accurately detect: 1. Significant grade VUR likely to alter clinical management 2. The presence of posterior urethral ballooning Assessed at the time of the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessed at the time of the intervention: 1. Image quality 2. Artifacts | — |
Countries
United Kingdom
Outcome results
None listed