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Effect of soy isoflavones and ascorbic acid supplementation on antioxidant activity in postmenopausal women

Effect of soy isoflavones and ascorbic acid supplementation on antioxidant activity in postmenopausal women: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN98074661
Enrollment
10
Registered
2005-02-24
Start date
2002-01-01
Completion date
Unknown
Last updated
2017-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antioxidant markers and risk factors for heart disease Signs and Symptoms Antioxidant markers and risk factors for heart disease

Interventions

Ten subjects were assigned to one of four dietary treatments: 1. Supplement of 5 mg isoflavones per kg/body weight (IF) 2. 500 mg vitamin C supplement (VC) 3. Supplement of 5 mg isoflavones per kg/bod

Sponsors

Arizona State University - Sustainable Technologies, Agribusiness and Resource Center (USA)
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Healthy, nonsmoking, postmenopausal women were screened for regular soy consumption (less than or equal to one serving per day), vitamin C supplementation (less than or equal to 60 mg/day), and postmenopausal status (one year).

Exclusion criteria

Exclusion criteria: 1. Vegetarianism 2. Current or past diagnosis of cancer 3. Cardiovascular disease or diabetes 4. Chronic illness or inflammation 5. Gastrointestinal disorders 6. Recent (previous six months) use of antibiotics, and use of hypoglycaemic or hypolipidaemic medication 7. Body mass index (BMI) less than or equal to 35 kg/m^2 8. Consumed less than or equal to two alcoholic drinks per day

Design outcomes

Primary

MeasureTime frame
Lipid peroxides

Secondary

MeasureTime frame
1. Vitamin C 2. Total cholesterol, including LDL, HDL and Triglycerides (TG) 3. Blood pressure

Countries

United States of America

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026