Overweight or obese with impaired glucose regulation Nutritional, Metabolic, Endocrine Obesity
Conditions
Interventions
Intervention - 12 weeks
Participants were advised not to change their habitual diet or their other lifestyle habits during the intervention. If they had been physically active during their leisure tim
Sponsors
Turku University of Applied Sciences (Finland)
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Male 2. 40-65 year old 3. Have a body mass index >25.1 ? 34.9 kg/m2 4. Obtain >12 points on the Finnish diabetes risk test 5. Have a plasma glucose 5.6?6.9 mmol/l and/or 2 hour plasma glucose 7.8?11 mmol/l 6. Have no other metabolic diseases 7. Passed medical examination
Exclusion criteria
Exclusion criteria: 1. Previously detected impaired fasting glucose or impaired glucose regulation and engaging in prescribed diet or exercise program 2. Engaged in regular and physically very vigorous activities 3. Use a medication affecting glucose balance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Impaired glucose tolerance from plasma blood samples with WHO criteria, measured at baseline and follow-up at 12, 26, and 52 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Glucose, adiponectin, leptin, tumor necrosis factor (TNF)-a, interleukin (IL)-6, gamma glutamyltransferase (gamma-GT), total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipopotein (LDL) cholesterol, triacylglycerols, and uric acid from the blood plasma samples 2. Insulin, Chemerin and RPB-4 from blood serum samples 3. Glycated haemoglobin (HbA1c) and serum high-sensitive C-reactive protein (CRP) with routine standardized methods 4. Blood pressure with standard procedures using automated device 5. Waist circumference, midway between spinailiaca superior and the lowest rib margin 6. Total body fat mass, fat-free mass, fat percentage by bioelectrical bioimpedance to the nearest 0.1 kg 7. Maximum oxygen uptake with direct maximal continuous incremental cycle ergometry until exhaustion or subjective maximum, measured at 0 and 3 months. 8. Maximum oxygen uptake, UKK fitness index, walking speed with a 2-km UKK walk test 9. Standing vertical jump height and counter-movement vertical jump height, with contact mat 10. Grip strength with dynamometry Data will be collected at baseline and follow-up at 12, 26 and 52 weeks | — |
Countries
Finland
Outcome results
None listed