Cognitive fatigue in children and young people (CYP) with acquired brain injury (ABI) Injury, Occupational Diseases, Poisoning
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children and young people (CYP) with ABI: 1. Fatigue problems (self-reported, parent-reported or clinical findings) due to moderate to severe ABI 2. Receiving follow-up care at Birmingham Children's Hospital (BCH), with a consensus clinical diagnosis of ABI from any aetiology (i.e. traumatic or non-traumatic injury or oncology) Control participants: 1. Typical developmental history 2. No known history of neurological conditions 3. Free from any medical conditions that required medical or surgical intervention within the last 6 months Both groups: 1. Aged between 10 and 18 years 2. Ability to communicate verbally or non-verbally with their parents and researchers if they don’t feel comfortable or report any problems while undergoing MRI 3. Commitment to engage in the assessments 4. CYP with neurodiversity (e.g., autism, attention deficit hyperactive disorder) diagnosis will be considered if parents feel that they can undergo the assessments
Exclusion criteria
Exclusion criteria: Control participants: 1. History of neurological conditions 2. History of neurodevelopmental conditions Both groups: 1. Suspected or confirmed alcohol/recreational substance use 2. Suspected or confirmed pregnancy 3. Parents who lack the capacity to consent 4. MRI incompatible: metal plates incompatible with MRI scanners, pacemakers, inability to lay flat for prolonged periods, aneurysm clips, neurostimulators, brain/subdural electrodes, etc
Countries
England, United Kingdom