Finding the Optimal Resistance Training Exercise for type 2 diabetes

Finding the optimal volume and intensity of resistance training exercise for type 2 diabetes: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN97865321

Enrollment

120

Registered

2010-06-21

Start date

2006-05-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus

Interventions

Six months of aerobic and resistance training: 1. Aerobic training and minimal resistance training (usual care) 2. Aerobic training and high intensity resistance training 3. Aerobic training and low

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults aged greater than 18 years, either sex 2. Type 2 Diabetes 3. Participating in the Diabetes Exercise and Healthy Lifestyle Program of the Toronto Rehabilitation Institute

Exclusion criteria

Exclusion criteria: 1. History of diagnosed cardiovascular disease 2. Contraindications to high intensity exercise participation: 2.1. Glaucoma 2.2. Retinopathy 2.3. Musculoskeletal limitations 2.4. Kidney disease 2.5. Balance impairments

Design outcomes

Primary

Measure	Time frame
Measured at baseline and 6 months: 1. HbA1c 2. Maximal aerobic power (VO2 max)	—

Secondary

Measure	Time frame
Measured at baseline and 6 months: 1. Fasting glucose 2. Insulin 3. Proinsulin 4. Blood lipid profile 5. Body composition (dual energy x-ray absorptiometry [DEXA]) 6. Cytokines (interleukin-6 [IL-6], interleukin-1B [IL-1B], c-reactive protein [CRP]) 7. Adipokines (tumour necrotising factor-alpha [TNF-alpha], adiponectin, leptin, leptin receptor) 8. Depressive mood (Center for Epidemiologic Studies Depression Scale [CESD]) 9. Quality of life (Diabetes Quality of Life Clinical Trial Questionnaire [DSQLQ]) 10. Nutrition intake	—

Measure

Time frame

Measured at baseline and 6 months: 1. Fasting glucose 2. Insulin 3. Proinsulin 4. Blood lipid profile 5. Body composition (dual energy x-ray absorptiometry [DEXA]) 6. Cytokines (interleukin-6 [IL-6], interleukin-1B [IL-1B], c-reactive protein [CRP]) 7. Adipokines (tumour necrotising factor-alpha [TNF-alpha], adiponectin, leptin, leptin receptor) 8. Depressive mood (Center for Epidemiologic Studies Depression Scale [CESD]) 9. Quality of life (Diabetes Quality of Life Clinical Trial Questionnaire [DSQLQ]) 10. Nutrition intake

—

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026