Disruptive mood and emotional conflict resolution in adolescent children of parents with recurrent depression or bipolar disorder and healthy controls

Rates of psychopathology including Disruptive Mood Dysregulation Disorder and emotional conflict resolution among adolescent children of parents with recurrent Major Depressive Disorder versus those with Bipolar Disorder and matched healthy controls

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN97724780

Enrollment

Registered

2015-08-20

Start date

2015-07-27

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disruptive Mood Dysregulation Disorder Mental and Behavioural Disorders

Interventions

Parents' psychological status is evaluated with Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). All parents will then complete SCL-90R, State-Trait Anxiety Inventory- Trait Version

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: For parents (in unipolar/bipolar groups): 1. Aged between 30- 65 years 2. Recurrent Major Depressive Disorder or Bipolar I/ II diagnosis (ascertained via SCID- I), 3. Followed at the outpatient department of Psychiatry of Abant Izzet Baysal University Medical Faculty, 4. Are in remission (CGI-S = 2, YMRS = 5, HAM-D-17 = 7) For parents in control group: 1. Have brought their adolescent offspring for acute somatic symptoms to the pediatrics outpatient department of Abant Izzet Baysal University Medical Faculty within the study period 2. Are free of lifetime psychopathology (ascertained via SCID-I)

Exclusion criteria

Exclusion criteria: For parents (in unipolar/bipolar groups): 1. Active disorder (CGI-S > 2, YMRS > 5, HAM-D-17 > 7) 2. Epilepsy/chronic neurological disorders/mental retardation 3. Active psychotic symptoms 4. Illiteracy For parents in control group: 1. Life time history of psychopathology 2. Epilepsy/chronic neurological disorders/mental retardation 3. Illiteracy For adolescent offspring: 1. Epilepsy/chronic neurological disorders/mental retardation 2. Illiteracy

Design outcomes

Primary

Measure	Time frame
Reaction speed of adolescents in three groups (unipolar offspring, bipolar offspring, healthy controls) in emotional stroop trials (in milliseconds)	—

Secondary

Measure	Time frame
1. Reaction speeds of adolescents in three groups (unipolar offspring, bipolar offspring, healthy controls) in Stroop Color Word Test - TBAG Form (in milliseconds) 2. Rates of psychopathologies (including DMDD) according to structured interviews (K-SADS-PL)	—

Countries

Turkey

Contacts

Public ContactZehra Topal

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026