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Perioperative pulmonary rehabilitation in thoracic surgery

The effectiveness of pulmonary rehabilitation on functional and quality of life parameters and tumor biological response in the PERIOPREPULMHAB study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN97596271
Enrollment
450
Registered
2017-11-06
Start date
2016-11-30
Completion date
Unknown
Last updated
2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer, lung abscess, COPD, interstitial lung disease, tuberculosis Respiratory Lung cancer, lung abscess, COPD, interstitial lung disease, tuberculosis

Interventions

This study tests the effectiveness of pulmonary rehabilitation on chest kinematics, lung mechanics, lung function, metabolism, peripherial and respiratory muscle function, exercise physiology, tumor b

Sponsors

National Koranyi Institute for Pulmonology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with COPD or interstitial lung disease 2. 30<Age<80 years 3. Able to perform respiratory training and endurance training 4. Able to understand the meaning of the program 5. Without significant psychological disease, which has influence the outcome of the rehabilitation

Exclusion criteria

Exclusion criteria: 1. Inoperable lung cancer because of oncological staging 2. Not able to perform the pulmonary rehabilitation program because of joint disease 3. Not able to perform the pulmonary rehabilitation program because of psychological disorder

Design outcomes

Primary

MeasureTime frame
1. Improvement of lung function is measured using spirometry the at end of rehabilitation and six and 12 months after the operation 2. Oxygen uptake is measured using the cardiopulmonary exercise test at the end of the rehabilitation and at 6 and 12 months after the operation 3. Metabolism at the end of the rehabilitation is measured using the cardiopulmonary exercise test at the end of the rehabilitation and at six and 12 months after the operation 4. Complications of the thoracic operation at 2 weeks after the thoracic surgery can be observed and at six and 12 months after the operation 5. Tumor biological response is measured using different analytical methods at six and 12 months after the operation

Secondary

MeasureTime frame
1. Chest kinematics is measured using thoracic circumference at the end of the rehabilitation and at 6 and 12 months after the operation 2. Lung mechanics is measured using lung function at the end of the rehabilitation and at 6 and 12 months after the operation 3. Peripheral and respiratory muscle function is measured using grip strength and peripherial muscle force measurement at the end of the rehabilitation and at 6 and 12 months after the operation 4. Quality of life is measured using CAT marker and mMRC at the end of the rehabilitation and at 6 and 12 months after the operation

Countries

Hungary

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 14, 2026